
When their trip to San Lorenzo takes a turn for the worst, Arnold and his classmate’s only hope of getting home is retracing the dangerous path that led to Arnold's parents' disappearance.
Cast

Mason Cotton
Arnold (voice)

Benjamin Flores Jr.
Gerald (voice)

Francesca Marie Smith
Helga (voice)

Anndi McAfee
Phoebe (voice)

Carlos Alazraqui
Eduardo (voice)

Alfred Molina
La Sombra (voice)

Justin Shenkarow
Harold (voice)
Antoinette Stella
Stella (voice)

Laya DeLeon Hayes
Nadine (voice)

Jamil Walker Smith
Paulo (voice)

Nika Futterman
Olga (voice)

Olivia Hack
Rhonda (voice)

Lane Toran
Che (voice)

Dan Butler
Mr. Simmons (voice)

Dan Castellaneta
Grandpa (voice)

Tress MacNeille
Grandma (voice)

Maurice LaMarche
Bob Pataki (voice)

Dom Irrera
Ernie (voice)

Kath Soucie
Miriam (voice)

Danielle Judovits
Big Patty (voice)

Danny Cooksey
Stoop Kid (voice)

Jim Belushi
Coach Wittenberg (voice)

Craig Bartlett
Miles (voice)

Gavin Lewis
Eugene (voice)

Jet Jurgensmeyer
Stinky (voice)

Aiden Lewandowski
Sid (voice)

Nicolas Cantu
Curly (voice)

Wally Wingert
Oskar (voice)

Stephen Stanton
Pigeon Man (voice)
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