
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
Cast

Jake Gyllenhaal
Jamie Randall

Anne Hathaway
Maggie Murdock

Oliver Platt
Bruce Winston

Hank Azaria
Dr. Stan Knight

Josh Gad
Josh Randall

Gabriel Macht
Trey Hannigan

Judy Greer
Cindy

Jill Clayburgh
Nancy Randall

George Segal
Dr. James Randall

Kate Jennings Grant
Gina

Katheryn Winnick
"Lisa"

Kimberly Scott
Gail

Peter Friedman
California Man

Nikki DeLoach
Christy

Natalie Gold
Dr. Helen Randall

Megan Ferguson
Farrah

Michael Benjamin Washington
Richard

Bingo O'Malley
Sam

Dorothy Silver
Sophie
Lucy Roucis
UN Convention Parkinson's Speaker
Joan Augustin
Joan

Michael Chernus
Jerry

Kate Easton
Amber

Michael Buffer
Pfizer Convention MC

Maïté Schwartz
Texas

Maximilian Osinski
Ned

Ian Harding
Pfizer Trainee #1

Josh Breslow
Pfizer Trainee #2

Ian Novick
Pfizer Trainee #3

Tess Soltau
Pfizer Trainee #4

Constance Brenneman
Pfizer Trainee #5
Nicole Thomas
Pfizer Trainee #6
Jasper Soffer
Pfizer Trainee #7
Kwame Rakes
Doctor in Parking Lot

Scott Cohen
Ted Goldstein

Sharon Wilkins
La Boheme Receptionist

Brian Hutchison
Homeless Man

Dana Dancho
Smiling Receptionist

Lisa Ann Goldsmith
Nurse Janice

Rick Applegate
Viagra Doctor
Ray Godshall Sr.
Friendly Senior
Jean Zarzour
Viagra Sample Nurse
Harry O'Toole
Man with Walker

Jennifer Delaeo
Viagra Receptionist

Deidre Goodwin
Viagra Nurse #1

Geneva Carr
Viagra Nurse #2

Vanessa Aspillaga
Viagra Nurse #3
Patricia Cray
Kindly-looking Woman

Kristin Spatafore
Convention Girl #1

Larissa Emanuele
Convention Girl #2

Loretta Higgins
PET Scan Doctor
Kimberly M. Rizzo
Front Desk Receptionist
Jason Bernard
Quack Doctor
Nicole Perrone
Determined Receptionist

Jo Newman
Bree
Christina Fandino
Khae

Teri Clark
ER Receptionist

Kevin McClatchy
Justin

Jaimie Alexander
Carol (uncredited)
Diedra Arthur-O'Ree
Medical Convention Attendee (uncredited)
Stephanie Bankosh
Pharmaceutical Rep (uncredited)
David Barckhoff
Medical Convention Vendor (uncredited)
Robert R. Bell
Doctor (uncredited)

Aaron Bernard
Bartender (uncredited)
Ralph Browning
Medical Convention Attendee (uncredited)
Alissa Collins
Tea Woman (uncredited)
Kyle Fields
Party Rep (uncredited)
Joe Forgione
Pfizer Trainee #8 (uncredited)
Nicole George
Viagra Receptionist (uncredited)
Ryan Goimarac
Pfizer Drug Rep. Graduate (uncredited)
Mark Golik
Physician (uncredited)

John W. Iwanonkiw
Viagra Guy (uncredited)

Sharyn Kmieciak
UN Convention Attendee (uncredited)
Wayne Leya
UN Convention Attendee (uncredited)
David Dale McCue
Pfizer Rep. (uncredited)
David Morse
Tony Lerma, Lilly Sales Rep. (uncredited)
Christian Pearson
Physician (uncredited)
Chris A. Riskus
Trade Show Patron (uncredited)
Nayli Russo
PJ Party Girl (uncredited)
Michael K. Sieg
Pfizer Rep. (uncredited)

Morgan Wolk
Lilly Spokesmodel (uncredited)

Conan O'Brien
Self (archive footage) (uncredited)
Gwyneth E. Larsen
Dancer (as Gwyneth Larsen)
Brooke Miyasaki
Dancer
Jackson Nunn
Viagra Guy #2 (uncredited)
Crew

Edward Zwick
Director, Screenplay, Producer
Charles Randolph
Screenplay, Producer

Marshall Herskovitz
Screenplay, Producer
Jamie Reidy
Book

Steven Rosenblum
Editor

Steven Fierberg
Director of Photography
Darin Rivetti
First Assistant Director, Associate Producer
Francesco Tignini
Second Assistant Director
Robb Earnest
Production Coordinator
Margaret Riley
Executive Producer

Arnon Milchan
Executive Producer

Julie M. Anderson
Production Supervisor

Scott Stuber
Producer

Pieter Jan Brugge
Producer, Unit Production Manager
Noam Dromi
Producer
Troy Putney
Associate Producer
Patti Podesta
Production Design
Chris Hayes
"A" Camera Operator
Rick Davidson
"B" Camera Operator
Dino Parks
Aerial Camera

Missy Finnell
Casting Assistant

Krysti Baxter
Casting Assistant

Stephanie Yankwitt
Casting Assistant
Yesi Ramirez
Casting Associate

Victoria Thomas
Casting
Mele Nagler
Casting
Donna M. Belajac
Casting
Amy Arnold
Costume Supervisor

Deborah L. Scott
Costume Design
Cheryl Daniels
Key Hair Stylist
Jerry Popolis
Hairstylist
Karen Lovell
Hairstylist
Linda Williams
Hairstylist
Nancy Keslar
Hairstylist
Geri Mataya
Hairstylist
Alan D'Angerio
Hairstylist
Elaine L. Offers
Makeup Department Head, Makeup Artist

Vivian Baker
Key Makeup Artist, Makeup Artist
Rachel Kick
Makeup Artist

Peter Swords King
Makeup Artist
Patty Bell
Makeup Artist
Christopher Patrick
Makeup Artist
Vickie Toner
Art Department Coordinator
John A. Larsen
Supervising Sound Editor

Anna Behlmer
Sound Re-Recording Mixer

Andy Nelson
Sound Re-Recording Mixer
Edward Tise
Sound Mixer
Ray Bivins
Special Effects Coordinator
Alan Munro
Visual Effects Supervisor
Brian Jochum
Visual Effects Producer
Jon Terada
VFX Artist
Daren Dochterman
VFX Artist

James Newton Howard
Original Music Composer
Randall Poster
Music Supervisor
Jay B. Richardson
Music Editor
Meg Everist
Set Decoration
David James
Additional Still Photographer
Rebecca Robertson
Script Supervisor
Shawn Boyachek
Location Manager

Josh Slates
Location Scout
Jason Silvis
Stunts
Bill Young
Stunts

Peter Epstein
Stunts

Bobby Stewart
Stunts
Coleen M. Tracy
Stunts
Adam Wood
Stunts

Frédéric North
Stunts, Pilot

Jeffrey Jones
Stunt Driver
Sean P. McCarthy
Stunt Driver

Stephen A. Pope
Stunt Coordinator
G.A. Aguilar
Stunt Coordinator

Daniel Ezralow
Choreographer
Steven R. Mathis
Gaffer
Gary Kosko
Art Direction
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