
Andrew returns to his hometown for the funeral of his mother, a journey that reconnects him with past friends. The trip coincides with his decision to stop taking his powerful antidepressants. A chance meeting with Sam - a girl also suffering from various maladies - opens up the possibility of rekindling emotional attachments, confronting his psychologist father, and perhaps beginning a new life.
Cast

Zach Braff
Andrew Largeman

Natalie Portman
Sam

Ian Holm
Gideon Largeman

Peter Sarsgaard
Mark

Jean Smart
Carol

Armando Riesco
Jesse

Jackie Hoffman
Aunt Sylvia Largeman

Method Man
Diego

Alex Burns
Dave

Ron Leibman
Dr. Cohen

Jim Parsons
Tim

Michael Weston
Kenny

Ann Dowd
Olivia

Ato Essandoh
Titembay

Denis O'Hare
Albert

Trisha LaFache
Kelly

Geoffrey Arend
Karl Benson

George C. Wolfe
Restaurant Manager

Austin Lysy
Waiter

Gary Gilbert
Young Hollywood Guy

Jill Flint
Obnoxious Girl

Christopher Carley
Gleason Party Drunk

Amy Ferguson
Dana
Wynter Kullman
Pam

Debbon Ayer
Faye

Yvette Mercedes
Neurology Receptionist

Jayne Houdyshell
Mrs. Lubin

Soara-Joye Ross
Handi-World Cashier

Joe Bacino
Man Having Sex
Seth Michael May
Peeping Tom
Kenneth Graymez
Busboy
Ryan B. Moschetti
Teen in Hallway
Tracey Antosiweicz
Hooker
Ice
Arthur-the-Dog
Magoo
Masturbating Dog
Janine Strafaci
Herself - News 12 New Jersey News Anchor (voice) (archive footage)
Kurt Siegelin
Himself - News 12 New Jersey News Anchor (archive footage)
Crew

Zach Braff
Director, Screenplay

Myron Kerstein
Editor

Lawrence Sher
Director of Photography
Michael Hatzer
Color Timer

Stacey Sher
Executive Producer

Danny DeVito
Executive Producer

Michael Shamberg
Executive Producer
Richard Klubeck
Producer
William H. Brown
Producer
Dan Halsted
Producer

Gary Gilbert
Producer

Pamela Abdy
Producer
Ann Ruark
Line Producer

Judy Becker
Production Design

Avy Kaufman
Casting

Michael Wilkinson
Costume Design
Corinna Woodcock
Hairstylist
Gianna Sparacino
Hairstylist

Evelyne Noraz
Makeup Artist
Chad Fischer
Original Music Composer
Alexi Murdoch
Original Music Composer

Heather Loeffler
Set Decoration
Laura Ballinger
Art Direction
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